IP Portfolio licensable from CAMBIA
Biological Gene Transfer System for Eukaryotic Cells (TransBacter™)
Microbial genes for secreted β-glucuronidases, gene products and uses thereof (GUSPlus™)
β-Glucuronidase (GUS) and Glucuronide Permease Gene System
Chimeric Genes - Gene Fusion Comprising Glucuronidase (gus)
A Gene Coding for Glucuronide Permease
Glucuronide Repressors and Uses Thereof
Preparation of Cellobiuronic Acid from Polysaccharide
Vertebrate Telomerase and Splice Variants
Methods for Site-Associated Modification of Gene Activity and Nucleic Acid (Trans-activation or TARGET™)
Megagametophyte-specific Transcriptional Control Elements and Uses Thereof
Fungal β-glucuronidase Genes and Gene Products
Methods for Genotyping by Hybridization Analysis (Diversity Arrays Technology, DArT™)
A Gene Coding for Glucuronide Permease
The invention relates to the gene encoding the transport protein glucuronide permease. Expression of glucuronide permease in transformants allows cellular uptake of β-glucuronides. This system can conveniently be used together with GUS gene fusions because it permits the detection of β-glucuronidase activity in vivo. In addition, glucuronide permease also can be used in a method to selectively alter the permeability of cells. Because of the variety of substances that can be conjugated to β-glucuronides, glucuronide permease provides cellular entrance for a multitude of compounds. Issued in Australia as Patent Number 620827. Issued in Denmark as PR173224, in France, Belgium, and Germany as 3,853,955, and in Italy, the Netherlands, Switzerland and Sweden as Patent Number 0383808. Issued in Great Britain as GB 2229184.
Licenses for both research and commercial use are available by contacting licenses@cambia.org.
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